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Article

DNA Damage Repair Pathways in Cancer Stem Cells

27 Jul 2012

Abstract excerpt

The discovery of tumor-initiating cells endowed with stem-like features has added a further level of complexity to the pathobiology of neoplastic diseases. In the attempt of dissecting the functional properties of this uncommon cellular subpopulation, investigators are taking full advantage of a body of knowledge about adult stem cells, as the "cancer stem cell model" implies that tissue-resident stem cells are...

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PMID: 22844074
DOI: 10.1158/1535-7163.mct-11-1040

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