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Article

ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.

Nature - 25 Jul 2012

Hashimoto Tatsuo, Perlot Thomas, Rehman Ateequr, Trichereau Jean, Ishiguro Hiroaki, Paolino Magdalena, Sigl Verena, Hanada Toshikatsu, Hanada Reiko, Lipinski Simone, Wild Birgit, Camargo Simone M R, Singer Dustin, Richter Andreas, Kuba Keiji, Fukamizu Akiyoshi, Schreiber Stefan, Clevers Hans, Verrey Francois, Rosenstiel Philip, Penninger Josef M

Abstract excerpt

Malnutrition affects up to one billion people in the world and is a major cause of mortality. In many cases, malnutrition is associated with diarrhoea and intestinal inflammation, further contributing to morbidity and death. The mechanisms by which unbalanced dietary nutrients affect intestinal h...

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Identifiers

PMID: 22837003
DOI: 10.1038/nature11228
PMCID: PMC7095315

Genes

ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22837003-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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