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Article

Expansion of mesenchymal stem cells on electrospun scaffolds maintains stemness, mechano-responsivity, and differentiation potential.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Feb 2018

Heo Su-Jin, Szczesny Spencer E, Kim Dong Hwa, Saleh Kamiel S, Mauck Robert L

Abstract excerpt

Mesenchymal stem cells (MSCs) hold great promise for regenerative therapies and tissue engineering applications given their multipotential differentiation capacity. However, MSC isolation and expansion are typically performed on super-physiologically stiff tissue culture plastic (TCP), which may alter their behavior and lead to unintended consequences upon implantation. In contrast, electrospun nanofibrous...

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Identifiers

PMID: 29027711
DOI: 10.1002/jor.23772
PMCID: PMC5839953

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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