Initiation of growth in pbpAts and rodAts mutants of Escherichia coli.

doi:10.1016/0378-1097(90)90378-4

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Article

Initiation of growth in pbpAts and rodAts mutants of Escherichia coli.

FEMS microbiology letters - 1 Oct 1990

Rodriguez M C, de Pedro M A

Abstract excerpt

Escherichia coli strains harbouring pbpAts mutations are particularly sensitive to functional alterations of penicillin-binding protein 2 (PBP 2) at the initiation of growth. Shift-up to 42 degrees C results in the inability of cells to reach a steady rate of growth and division. Furthermore, a very high proportion of cells generate minicell-like structures which are pinched-off through a process requiring the...

Topics

Azlocillin
Bacterial Proteins
Carrier Proteins
Escherichia coli
Escherichia coli Proteins
Hexosyltransferases
Imidazolidines
Kinetics
Membrane Proteins
Multienzyme Complexes
Muramoylpentapeptide Carboxypeptidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Penicillin-Binding Proteins

Penicillins

Peptidoglycan Glycosyltransferase

Peptidyl Transferases

Temperature

Source

Open in PubMed

Identifiers

PMID: 2283038
DOI: 10.1016/0378-1097(90)90378-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2283038-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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