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Article

Association between polymorphisms in DNA repair genes (XRCC1 and XRCC7) and risk of preeclampsia.

Archives of gynecology and obstetrics - 1 Dec 2012

Saadat Iraj, Beyzaei Zahra, Aghaei Fatemeh, Kamrani Sedighe, Saadat Mostafa

Abstract excerpt

PURPOSE: Although the exact genes involved in preeclampsia (PE) are still not fully discovered, an important role for oxidative stress in its pathogenesis is accepted. XRCC1 (MIM: 194360) and XRCC7 (MIM: 600899) play a crucial role in the DNA repair pathways. Functional polymorphisms in XRCC1 (Arg194Trp and Arg399Gln) and XRCC7 (G6721T) may be risk factors for PE. In the present study, the association between the...

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Identifiers

PMID: 22825692
DOI: 10.1007/s00404-012-2471-7

Genes

XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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