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Article

Association between polymorphisms rs2228001 and rs2228000 in XPC and genetic susceptibility to preeclampsia: a case control study.

BMC pregnancy and childbirth - 22 Nov 2021

Wang Jingli, Guan Chengcheng, Sui Jing, Zang Yucui, Wu Yuwen, Zhang Ru, Qi Xiaoying, Piao Shunfu

Abstract excerpt

BACKGROUND: Xeroderma pigmentosum complementation group C (XPC) is a DNA damage recognition protein that plays an important role in nucleotide excision repair and can reduce oxidative stress, which may be involved in the development of preeclampsia (PE). Therefore, the aim of this study was to explore whether XPC polymorphisms were relevant to the genetic susceptibility to PE in Chinese Han women. METHOD: A total...

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Identifiers

PMID: 34802422
DOI: 10.1186/s12884-021-04242-1
PMCID: PMC8607566

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