Article
New pieces of a puzzle: the current biological picture of MPN.
Biochimica et biophysica acta - 1 Dec 2012
Kleppe Maria, Levine Ross L
Abstract excerpt
Over the last years, we have witnessed significant improvement in our ability to elucidate the genetic events, which contribute to the pathogenesis of acute and chronic leukemias, and also in patients with myeloproliferative neoplasms (MPN). However, despite significant insight into the role of specific mutations, including the JAK2V617F mutation, in MPN pathogenesis, the precise mechanisms by which specific...
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