Article
Metallothionein 2A genetic polymorphisms and risk of prostate cancer in a Polish population.
Cancer genetics - 1 Sept 2012
Forma Ewa, Krzeslak Anna, Wilkosz Jacek, Jozwiak Pawel, Szymczyk Agnieszka, Rozanski Waldemar, Brys Magdalena
Abstract excerpt
Metallothionein 2A (MT2A) is the most expressed metallothionein (MT) isoform in prostate cells. A number of studies have demonstrated altered MT2A expression in various human tumors, including prostate cancer. We conducted an association study to examine whether MT2A gene polymorphisms are associated with a risk of prostate cancer. Genotyping was conducted using a polymerase chain reaction-restriction fragment...
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