Effect of metallothionein 2A gene polymorphism on allele-specific gene expression and metal content in prostate cancer.

doi:10.1016/j.taap.2013.02.013

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Article

Effect of metallothionein 2A gene polymorphism on allele-specific gene expression and metal content in prostate cancer.

Toxicology and applied pharmacology - 1 May 2013

Krześlak Anna, Forma Ewa, Chwatko Grażyna, Jóźwiak Paweł, Szymczyk Agnieszka, Wilkosz Jacek, Różański Waldemar, Bryś Magdalena

Abstract excerpt

Metallothioneins (MTs) are highly conserved, small molecular weight, cysteine rich proteins. The major physiological functions of metallothioneins include homeostasis of essential metals Zn and Cu and protection against cytotoxicity of heavy metals. The aim of this study was to determine whether there is an association between the -5 A/G single nucleotide polymorphism (SNP; rs28366003) in core promoter region and...

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PMID: 23466427
DOI: 10.1016/j.taap.2013.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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