Article
Runx2 isoform I controls a panel of proinvasive genes driving aggressiveness of papillary thyroid carcinomas.
The Journal of clinical endocrinology and metabolism - 1 Oct 2012
Sancisi Valentina, Borettini Gloria, Maramotti Sally, Ragazzi Moira, Tamagnini Ione, Nicoli Davide, Piana Simonetta, Ciarrocchi Alessia
Abstract excerpt
CONTEXT: The ability of tumor cells to invade adjacent tissues is governed by a complicated network of molecular signals, most of which have not yet been identified. In a recent work, we reported that the transcriptional regulator Id1 contributes to thyroid cancer progression by powering the invasion capacity of tumor cells. OBJECTIVE: The intent of this work was to further investigate the biology of invasive...
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