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Article

Influence of main channel structure on H(2)O(2) access to the heme cavity of catalase KatE of Escherichia coli.

Archives of biochemistry and biophysics - 1 Oct 2012

Jha Vikash, Chelikani Prashen, Carpena Xavi, Fita Ignacio, Loewen Peter C

Abstract excerpt

The main channel for H(2)O(2) access to the heme cavity in large subunit catalases is twice as long as in small subunit catalases and is divided into two distinct parts. Like small subunit catalases, the 15Å of the channel adjacent to the heme has a predominantly hydrophobic surface with only weak water occupancy, but the next 15Å extending to the protein surface is hydrophilic and contains a complex water matrix...

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Identifiers

PMID: 22820098
DOI: 10.1016/j.abb.2012.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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