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Article

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity.

Cancer research - 15 Sept 2012

Leandro-García Luis J, Leskelä Susanna, Inglada-Pérez Lucía, Landa Iñigo, de Cubas Aguirre A, Maliszewska Agnieszka, Comino-Méndez Iñaki, Letón Rocío, Gómez-Graña Álvaro, Torres Raúl, Ramírez Juan Carlos, Álvarez Sara, Rivera José, Martínez Constantino, Lozano María Luisa, Cascón Alberto, Robledo Mercedes, Rodríguez-Antona Cristina

Abstract excerpt

Cellular microtubules composed of α-β-tubulin heterodimers that are essential for cell shape, division, and intracellular transport are valid targets for anticancer therapy. However, not all the conserved but differentially expressed members of the β-tubulin gene superfamily have been investigated for their role in these settings. In this study, we examined roles for the hematologic isoform β-tubulin VI and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22805305
DOI: 10.1158/0008-5472.CAN-11-2861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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