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Article

Epistasis and immunity: the role of genetic interactions in autoimmune diseases.

Immunology - 1 Oct 2012

Rose Anna M, Bell Lucy C K

Abstract excerpt

Autoimmune disorders are a complex and varied group of diseases that are caused by breakdown of self-tolerance. The aetiology of autoimmunity is multi-factorial, with both environmental triggers and genetically determined risk factors. In recent years, it has been increasingly recognized that genetic risk factors do not act in isolation, but rather the combination of individual additive effects, gene-gene...

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Identifiers

PMID: 22804709
DOI: 10.1111/j.1365-2567.2012.03623.x
PMCID: PMC3461394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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