Article
Synergistic roles of scleraxis and Smads in the regulation of collagen 1α2 gene expression.
Biochimica et biophysica acta - 1 Oct 2012
Bagchi Rushita A, Czubryt Michael P
Abstract excerpt
Cardiac fibrosis is marked by increased deposition of extracellular matrix components including fibrillar collagens, leading to impaired cardiac contractility and function. We recently demonstrated that the transcription factor scleraxis is expressed in collagen-producing cardiac fibroblasts and...
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