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Article

Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study.

Archives of Iranian medicine - 1 Sept 2010

Heidari Javad, Akrami Seyed Mohammad, Heshmat Ramin, Amiri Parvin, Fakhrzadeh Hossein, Pajouhi Mohammad

Abstract excerpt

BACKGROUND: A functional polymorphism in the uncoupling protein 2 (UCP2) gene promoter has been associated with obesity and type 2 diabetes (T2D) in some populations. The impact of UCP2 polymorphisms on diabetes and obesity is still under debate. Contradictory results have been reported in different populations world-wide. To clarify the contribution of the UCP2 gene -866 G/A polymorphism in the Iranian...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20804304
DOI: 010135/AIM.004

Genes

UCP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association study of the -866G/A UCP2 gene promoter polymorphism with type 2 diabetes and obesity in a Tehran population: a case control study.PMID 20804304Read ↗

A common polymorphism in the promoter of UCP2 is associated with obesity and hyperinsulenemia in northern Indians.Semantic proximity Read ↗

An association between -866G/A polymorphism in the promoter of UCP2 and obesity: a meta-analysis.Semantic proximity Read ↗

The common -866G/A polymorphism of the UCP2 gene in healthy Iranians compared with world populations.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphism - 866 G/A in the promoter region is associated with type 2 diabetes mellitus among Kashmiri population of Northern India.Semantic proximity Read ↗

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients.Semantic proximity Read ↗

A polymorphism in the promoter of UCP2 gene modulates lipid levels in patients with type 2 diabetes.Semantic proximity Read ↗

A common polymorphism of uncoupling protein 2 gene is associated with hypertension.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphism -866 G/A in the promoter region is associated with Type 2 Diabetes Mellitus among Kashmiri population of Northern IndiaSemantic proximity Read ↗

Unleash the Association of Mitochondrial Uncoupling Protein (UCP2) Promoter Variant (G-866A; rs659366) with Obesity: Stepping from a Case-Control Study to a Meta-analysis.Semantic proximity Read ↗

The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes.Semantic proximity Read ↗

The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy.Semantic proximity Read ↗

Mitochondrial uncoupling protein 2 (UCP2) gene polymorphisms are associated with childhood obesity and related metabolic disorders.Semantic proximity Read ↗

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