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Article

Mutations that alter RcdA surface residues decouple protein localization and CtrA proteolysis in Caulobacter crescentus.

Journal of molecular biology - 20 Nov 2009

Taylor James A, Wilbur Jeremy D, Smith Stephen C, Ryan Kathleen R

Abstract excerpt

Periodic activation and deactivation of the essential transcriptional regulator CtrA is necessary to drive cell cycle progression in Caulobacter crescentus. At the onset of DNA replication (the G1-S cell cycle transition), CtrA and the AAA+ protease ClpXP colocalize at one cell pole along with three accessory proteins, RcdA, CpdR, and PopA, and CtrA is rapidly degraded. RcdA is required for polar sequestration...

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Identifiers

PMID: 19747489
DOI: 10.1016/j.jmb.2009.08.076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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