Association of GNLY genetic polymorphisms with chronic liver disease in a Korean population.

Abstract excerpt

Granulysin (GNLY) is found in cytotoxic granules of cytolytic T lymphocytes and natural killer (NK) cells, which are critical for hepatitis B virus (HBV) clearance. GNLY cytotoxicity plays an important role in the defense against viruses or intracellular bacteria. We hypothesized that genetic variation in the GNLY gene could affect the resistance of hosts against HBV infection. We compared the distribution...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antigens, Differentiation, T-Lymphocyte
• Share to Asian People