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Apoptosis in temporomandibular joint disc with internal derangement involves mitochondrial-dependent pathways. Anin vivostudy

12 Jul 2012

Abstract excerpt

OBJECTIVE: Two main apoptosis pathways have been identified: an extrinsic (or death receptor-mediated) and an intrinsic (or mitochondrial) pathway. Apoptotic cell death through the extrinsic pathway has just been described in temporomandibular joint disc (TMJ) with internal derangement (ID); in contrast, no data are available on the involvement of the intrinsic pathway in this tissue. The aim of this work was to...

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PMID: 22783811
DOI: 10.3109/00016357.2012.700060

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