Apoptosis of human intervertebral discs after trauma compares to degenerated discs involving both receptor‐mediated and mitochondrial‐dependent pathways

Abstract excerpt

Post-traumatic disc degeneration with consecutive loss of reduction and kyphosis remains a debatable issue within both the operative and nonoperative treatment regimen of thoracolumbar spine fractures. Intervertebral disc (IVD) cell apoptosis has been suggested to play a vital role in promoting the degeneration process. To evaluate and compare apoptosis-regulating signaling mechanisms, IVDs were obtained from...

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