Article
Efficient sampling for Bayesian inference of conjunctive Bayesian networks.
Bioinformatics (Oxford, England) - 15 Sept 2012
Sakoparnig Thomas, Beerenwinkel Niko
Abstract excerpt
MOTIVATION: Cancer development is driven by the accumulation of advantageous mutations and subsequent clonal expansion of cells harbouring these mutations, but the order in which mutations occur remains poorly understood. Advances in genome sequencing and the soon-arriving flood of cancer genome data produced by large cancer sequencing consortia hold the promise to elucidate cancer progression. However, new...
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