Article
[Enrichment analysis of Fanconi anemia gene expression profiles in cancer related genesets].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 May 2012
Zhou Quan-quan, Wang Xiao-juan, Zhu Xiao-fan, Yuan Wei-ping, Cheng Tao
Abstract excerpt
OBJECTIVE: To investigate the underlying tumor susceptibility mechanisms and reasons for the high risk of cancer in Fanconi anemia (FA). METHODS: Gene Set Enrichment Analysis (GSEA) was performed to compare gene expression profiles between 21 FA patients' bone marrow (BM) mononuclear cell (BMNC) and 11 normal controls in cancer related gene sets from NCBI GEO database, then core enriched genes were identified by...
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