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Article

Expression and purification of full length mouse metal response element binding transcription factor-1 using Pichia pastoris.

Protein expression and purification - 1 Sept 2012

Huyck Ryan W, Keightley Andrew, Laity John H

Abstract excerpt

The metal response element binding transcription factor-1 (MTF-1) is an important stress response, heavy metal detoxification, and zinc homeostasis factor in eukaryotic organisms from Drosophila to humans. MTF-1 transcriptional regulation is primarily mediated by elevated levels of labile zinc, which direct MTF-1 to bind the metal response element (MRE). This process involves direct zinc binding to the MTF-1 zinc...

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Identifiers

PMID: 22780964
DOI: 10.1016/j.pep.2012.06.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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