Article
Association of FCRL4 polymorphisms on disease susceptibility and severity of ankylosing spondylitis in Chinese Han population.
Clinical rheumatology - 1 Oct 2012
Zeng Zhen, Duan Zhenhua, Zhang Tianchen, Wang Sheng, Li Guixing, Mei Yang, Gao Jing, Ge Rui, Ye Dongqing, Zou Yanfeng, Xu Shengqian, Xu Jianhua, Zhang Li, Pan Faming
Abstract excerpt
Previous studies have found that the Fc receptor-like (FCRL) molecule, involved in controlling B cell signaling, may contribute to the autoimmune disease process. Many studies have reported the relation of FCRL gene family with SLE and RA. We hypothesized that FCRL4 may be a key gene for ankylosing spondylitis (AS) development. To test this hypothesis, we screened FCRL4 polymorphisms in the Chinese Han...
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