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Article

Genotype networks shed light on evolutionary constraints.

Trends in ecology & evolution - 1 Nov 2011

Wagner Andreas

Abstract excerpt

An evolutionary constraint is a bias or limitation in phenotypic variation that a biological system produces. One can distinguish physicochemical, selective, genetic and developmental causes of such constraints. Here, I discuss these causes in three classes of system that bring forth many phenotypic traits and evolutionary innovations: regulatory circuits, macromolecules and metabolic networks. In these systems,...

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Identifiers

PMID: 21840080
DOI: 10.1016/j.tree.2011.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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