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Article

Genetic variation of XPA gene and risk of cancer: a systematic review and pooled analysis.

International journal of cancer - 15 Jul 2012

Ding Dapeng, Zhang Ying, Yu Hailang, Guo Yunbo, Jiang Ling, He Xiaofeng, Ma Wenli, Zheng Wenling

Abstract excerpt

XPA, a zinc-finger DNA-binding protein, play an important role in both global genome and transcription-coupled repair pathways. XPA -4G>A polymorphism was identified in the 5' noncoding region, located four nucleotides upstream of the ATG start codon. Previous studies have shown that this polymorphism may affect mRNA tertiary structure and stability and play a role in susceptibility to cancer. However, the...

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Source

Identifiers

PMID: 21866550
DOI: 10.1002/ijc.26391

Genes

XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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