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Article

Establishing mechanisms affecting the individual response to ionizing radiation

19 Dec 2019

Abstract excerpt

The IR-induced DNA damage response (DDR) has been well characterized. Patients with mutations in the DDR have been identified and display marked RS but they represent only a small percentage of the RT patients with adverse reactions. We review the impacting mechanisms and additional factors influencing RS/RSu. We discuss whether RS/RSu might be genetically determined. As a recommendation, we propose that a...

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PMID: 31852363
DOI: 10.1080/09553002.2019.1704908

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