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Article

Combined effects of CXCL8 and CXCR2 gene polymorphisms on susceptibility to systemic sclerosis.

Cytokine - 1 Nov 2012

Salim Patricia Hartstein, Jobim Mariana, Bredemeier Markus, Chies José Arthur Bogo, Brenol João Carlos Tavares, Jobim Luiz Fernando, Xavier Ricardo Machado

Abstract excerpt

UNLABELLED: A previous study suggested that the CXCR2 (+1208) TT genotype was associated with increased risk of systemic sclerosis (SSc). In the present study, we investigated the influence of variation in the CXCL8 and CXCR2 genes on susceptibility to SSc and combined the variant alleles of these genes to analyze their effects on SSc. METHODS: One fifty one patients with SSc and 147 healthy bone marrow donors...

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Source

Identifiers

PMID: 22763041
DOI: 10.1016/j.cyto.2012.05.026

Genes

CXCR2
CXCL8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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