Article
Real-time PCR-based genotyping assay for CXCR2 polymorphisms.
Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2004
Gupta Manish, Song Pengfei, Yates Charles R, Meibohm Bernd
Abstract excerpt
BACKGROUND: The human chemokine receptor CXCR2 (IL8RB) is a high affinity receptor for interleukin-8 as well as other CXC chemokines, and is involved in the chemotaxis of immune cells. Genetic variants of CXCR2 have potential relevance in various inflammatory human disorders. We developed a real-time polymerase chain reaction (PCR)-based allelic discrimination assay for the detection of the CXCR2 single...
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