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Article

RHD zygosity assignments based on most probable genotype and hybrid Rhesus box detection in Tunisia.

Transfusion medicine (Oxford, England) - 1 Oct 2012

Kacem Narjes, Chakroun Tahar, Moussa Hajer, Abdelkefi Saïda, Houissa Betoul, Chiaroni Jacques, Jemni Yacoub Saloua

Abstract excerpt

BACKGROUND: Determination of the RHD zygosity is important for genetic counselling and risk evaluation of hemolytic disease of the newborn HDN in women with D iso-immunisation. OBJECTIVES: We proposed to determine the genotype frequencies of the RHD locus using a PCR-SSP method and assignment of the most probable genotype (MPG) and analyse the concordance between the two methods. METHODS: The complete Rh...

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Identifiers

PMID: 22757646
DOI: 10.1111/j.1365-3148.2012.01172.x

Genes

RHD
MPG

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