Article
Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients.
Journal of bacteriology - 1 Sept 2012
Chung Jade C S, Becq Jennifer, Fraser Louise, Schulz-Trieglaff Ole, Bond Nicholas J, Foweraker Juliet, Bruce Kenneth D, Smith Geoffrey P, Welch Martin
Abstract excerpt
The airways of individuals with cystic fibrosis (CF) often become chronically infected with unique strains of the opportunistic pathogen Pseudomonas aeruginosa. Several lines of evidence suggest that the infecting P. aeruginosa lineage diversifies in the CF lung niche, yet so far this contemporary diversity has not been investigated at a genomic level. In this work, we sequenced the genomes of pairs of randomly...
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