Article
Association between cagA and vacA genotypes and pathogenesis in a Helicobacter pylori infected population from South-eastern Sweden.
BMC microbiology - 2 Jul 2012
Karlsson Anneli, Ryberg Anna, Dehnoei Marjan Nosouhi, Borch Kurt, Monstein Hans-Jürg
Abstract excerpt
BACKGROUND: Chronic gastritis, peptic ulcer disease, and gastric cancer have been shown to be related to infection with Helicobacter pylori (H. pylori). Two major virulence factors of H. pylori, CagA and VacA, have been associated with these sequelae of the infection. In this study, total DNA was...
Topics
- Antigens, Bacterial
- Bacterial Proteins
- Biopsy
- Gastric Mucosa
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Polymerase Chain Reaction
- Sequence Analysis, DNA
- Sweden
- Virulence Factors