Article
Common TGFβ2, BMP4, and FOXC1 variants are not associated with primary open-angle glaucoma.
Molecular vision - 1 Jan 2012
Park Soo, Jamshidi Yalda, Vaideanu Daniela, Fraser Scott, Sowden Jane C
Abstract excerpt
PURPOSE: Primary open-angle glaucoma (POAG) is a common but complex disease with a strong genetic component. Notably, few genes have been robustly associated with POAG. An obvious group of genes to test as susceptibility factors for POAG are the developmental genes forkhead box C1 (FOXC1), transforming growth factor-beta 2 (TGFβ2), and bone morphogenic protein 4 (BMP4). These genes are known to play important...
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