Article
Genome-wide association study of primary open angle glaucoma risk and quantitative traits.
Molecular vision - 1 Jan 2012
Gibson Jane, Griffiths Helen, De Salvo Gabriella, Cole Mick, Jacob Aby, Macleod Alex, Yang Yit, Menon Geeta, Cree Angela, Ennis Sarah, Lotery Andrew
Abstract excerpt
PURPOSE: Primary open angle glaucoma (POAG) is a characteristic optic neuropathy which progresses to irreversible vision loss. Few genes have been detected that influence POAG susceptibility and other genes are therefore likely to be involved. We analyzed carefully characterized POAG cases in a genome-wide association study (GWAS). METHODS: We performed a GWAS in 387 POAG cases using public control data (WTCCC2)....
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