Article
Variants in the SRD5A2 gene are associated with quality of semen.
Molecular medicine reports - 1 Sept 2012
Zhao Dan, Wu Wei, Xu Bin, Niu Xiaobing, Cui Hongxing, Zhang Yi, Wang Zengjun, Wang Xinru
Abstract excerpt
Spermatogenesis and sperm maturation are androgen-dependent processes. Steroid 5α-reductase (SRD5A) is a key enzyme converting testosterone into the more active metabolite, dihydrotestosterone (DHT). We aimed to investigate the association between the genetic variants of SRD5A2 (rs4952197, rs2268797, rs13395648, rs523349 and rs632148) and semen quality. Variant...