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Article

Impact of lopinavir/ritonavir use on antiretroviral resistance in recent clinical practice.

The Journal of antimicrobial chemotherapy - 1 Oct 2012

Lambert-Niclot Sidonie, Masquelier Bernard, Cohen Codar Isabelle, Soulie Cathia, Delaugerre Constance, Morand-Joubert Laurence, Charpentier Charlotte, Ferre Virginie, Plantier Jean-Christophe, Montes Brigitte, Carret Sophie, Perrot Valerie, Peytavin Gilles, Costagliola Dominique, Calvez Vincent, Marcelin Anne-Geneviève

Abstract excerpt

OBJECTIVES: This observational study was requested by French health authorities to determine the impact of lopinavir/ritonavir (Kaletra(®)) on antiretroviral resistance in clinical practice. Virological failures of lopinavir/ritonavir and their effects on the resistance to protease inhibitors and reverse transcriptase inhibitors were evaluated in protease inhibitor-experienced patients. PATIENTS AND METHODS:...

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Identifiers

PMID: 22733652
DOI: 10.1093/jac/dks226

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