Article
Lopinavir/ritonavir monotherapy after virologic failure of first-line antiretroviral therapy in resource-limited settings.
AIDS (London, England) - 17 Jul 2012
Bartlett John A, Ribaudo Heather J, Wallis Carole L, Aga Evgenia, Katzenstein David A, Stevens Wendy S, Norton Michael R, Klingman Karin L, Hosseinipour Mina C, Crump John A, Supparatpinyo Khuanchai, Badal-Faesen Sharlaa, Kallungal Beatrice A, Kumarasamy Nagalingeswaran
Abstract excerpt
OBJECTIVE: To evaluate virologic response rates of lopinavir/ritonavir (LPV/r) monotherapy as second-line antiretroviral treatment (ART) among adults in resource-limited settings (RLSs). DESIGN: An open-label pilot study of LPV/r monotherapy in participants on first-line nonnucleoside reverse transcriptase inhibitor three-drug combination ART with plasma HIV-1 RNA 1000-200 000 copies/ml. METHODS: Participants...
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