Article
Designing redox potential-controlled protein switches based on mutually exclusive proteins.
Protein science : a publication of the Protein Society - 1 Aug 2012
Peng Qing, Kong Na, Wang Hui-Chuan Eileen, Li Hongbin
Abstract excerpt
Synthetic/artificial protein switches provide an efficient means of controlling protein functions using chemical signals and stimuli. Mutually exclusive proteins, in which only the host or guest domain can remain folded at a given time owing to conformational strain, have been used to engineer novel protein switches that can switch enzymatic functions on and off in response to ligand binding. To further explore...
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