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Article

The yin and yang of claudin-14 function in human diseases.

Annals of the New York Academy of Sciences - 1 Jul 2012

Hou Jianghui

Abstract excerpt

Claudins are tight junction integral membrane proteins that are key regulators of the paracellular pathway. The paracellular pathways in the inner ear and in the kidney are predominant routes for transepithelial cation transport. Mutations in claudin-14 cause nonsyndromic recessive deafness DFNB29. A recent genome-wide association study has identified claudin-14 as a major risk gene of hypercalciuric...

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Identifiers

PMID: 22731732
DOI: 10.1111/j.1749-6632.2012.06529.x
PMCID: PMC3733995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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