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Article

Yeast artificial chromosomes: an alternative approach to the molecular analysis of mouse developmental mutations.

Genetical research - 1 Jan 2000

Larin Z, Lehrach H

Abstract excerpt

Mammalian genetics now allows a molecular study of genomic regions previously analysed by genetic and embryological techniques. To simplify such an analysis, we have established a number of libraries of mouse DNA in Yeast Artificial Chromosome (YAC) vectors, constructed either by partial digestion with EcoRI, or by complete digestion with enzymes which cut rarely in the mammalian genome. In this paper we report...

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Identifiers

PMID: 2272511
DOI: 10.1017/s0016672300035308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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