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Article

Yeast artificial chromosomes: an alternative approach to the molecular analysis of mouse developmental mutations.

Genetical research - 1 Jan 2000

Larin Z, Lehrach H

Abstract excerpt

Mammalian genetics now allows a molecular study of genomic regions previously analysed by genetic and embryological techniques. To simplify such an analysis, we have established a number of libraries of mouse DNA in Yeast Artificial Chromosome (YAC) vectors, constructed either by partial digestio...

Topics

Animals
Chromosomes, Fungal
Cloning, Molecular
Embryonic and Fetal Development
Gene Library
Genetic Vectors
Genomic Library
Male
Mice
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2272511
DOI: 10.1017/s0016672300035308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2272511-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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