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Article

Age at onset in Huntington's disease: replication study on the association of HAP1.

Parkinsonism & related disorders - 1 Nov 2012

Karadima Georgia, Dimovasili Christina, Koutsis Georgios, Vassilopoulos Demetris, Panas Marios

Abstract excerpt

In recent years two association studies investigating the HAP1 T441M (rs4523977) polymorphism as a potential modifying factor of the age at onset (AAO) of Huntington's disease (HD), have been reported. Initially evidence for association was found between the M441 risk allele and the AAO. Subseque...

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Source

Identifiers

PMID: 22698993
DOI: 10.1016/j.parkreldis.2012.05.020

Genes

HAP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22698993-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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