Article
Dopamine signaling is essential for precise rates of locomotion by C. elegans.
PloS one - 1 Jan 2012
Omura Daniel T, Clark Damon A, Samuel Aravinthan D T, Horvitz H Robert
Abstract excerpt
Dopamine is an important neuromodulator in both vertebrates and invertebrates. We have found that reduced dopamine signaling can cause a distinct abnormality in the behavior of the nematode C. elegans, which has only eight dopaminergic neurons. Using an automated particle-tracking system for the analysis of C. elegans locomotion, we observed that individual wild-type animals made small adjustments to their speed...
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