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Article

Treponema denticola superoxide reductase: in vivo role, in vitro reactivities, and a novel [Fe(Cys)(4)] site.

Biochemistry - 17 Jul 2012

Caranto Jonathan D, Gebhardt Linda L, MacGowan Charles E, Limberger Ronald J, Kurtz Donald M

Abstract excerpt

In vitro and in vivo results are presented demonstrating that superoxide reductase (SOR) from the air-sensitive oral spirochete, Treponema denticola (Td), is a principal enzymatic scavenger of superoxide in this organism. This SOR contains the characteristic non-heme [Fe(His)(4)Cys] active sites. No other metal-binding domain has been annotated for Td SOR. However, we found that Td SOR also accommodates a...

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PMID: 22715932
DOI: 10.1021/bi300667s
PMCID: PMC3447989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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