Article
Clomipramine vs desipramine vs placebo in the treatment of diabetic neuropathy symptoms. A double-blind cross-over study.
British journal of clinical pharmacology - 1 Nov 1990
Sindrup S H, Gram L F, Skjold T, Grodum E, Brøsen K, Beck-Nielsen H
Abstract excerpt
1. The effect of clomipramine and desipramine on diabetic neuropathy symptoms was examined in a double-blind, randomised, placebo controlled, cross-over study for 2 + 2 + 2 weeks. Drug doses were adjusted according to the sparteine phenotype, i.e. extensive metabolisers were treated with 75 mg cl...
Topics
- Adult
- Aged
- Clomipramine
- Desipramine
- Diabetic Neuropathies
- Double-Blind Method
- Drug Evaluation
- Female
- Humans
- Male
- Middle Aged
- Phenotype
- Sparteine