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Article

Clomipramine dose-effect study in patients with depression: clinical end points and pharmacokinetics. Danish University Antidepressant Group (DUAG).

Clinical pharmacology and therapeutics - 1 Aug 1999

Abstract excerpt

OBJECTIVE: To examine the problems of establishing dose-effect and concentration-effect relationships of antidepressant therapy with clomipramine. METHODS: This randomized double-blind study compared five fixed doses of clomipramine hydrochloride: 25, 50, 75, 125, and 200 mg/day in hospitalized or day patients at nine clinical centers in Denmark. A 1-week washout period was followed by 6 weeks of active treatment...

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Source

Identifiers

PMID: 10460069
DOI: 10.1016/S0009-9236(99)90053-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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