Article
Seasonal variation in expression of markers in the vitamin D pathway in prostate tissue.
Cancer causes & control : CCC - 1 Aug 2012
Epstein Mara M, Andrén Ove, Kasperzyk Julie L, Shui Irene M, Penney Kathryn L, Fall Katja, Rider Jennifer R, Stampfer Meir J, Andersson Swen-Olof, Giovannucci Edward, Mucci Lorelei A
Abstract excerpt
PURPOSE: Recent studies suggest variation in genes along the vitamin D pathway, as well as vitamin D receptor (VDR) protein levels, may be associated with prostate cancer. As serum vitamin D levels vary by season, we sought to determine whether the expression of genes on the vitamin D pathway, assessed in prostate tumor tissue, do the same. METHODS: Our study incorporates mRNA expression data from 362 men in the...
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