Article
The CLOCK 3111T/C SNP is associated with morning gastric motility in healthy young women.
Physiology & behavior - 20 Aug 2012
Yamaguchi Mitsue, Kotani Kazuhiko, Sakane Naoki, Tsuzaki Kokoro, Takagi Ayaka, Wakisaka Shiori, Moritani Toshio, Nagai Narumi
Abstract excerpt
Circadian locomotor output cycles kaput (CLOCK) molecule plays major roles in circadian rhythmicity and regulates daily physiological processes including digestive activity. Therefore, we hypothesized that the CLOCK 3111T/C single nucleotide polymorphism (SNP) might have adverse effects on the regulation of gastric motility. Based on the hypothesis, we investigated whether this SNP was associated with morning...
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