Article
CLOCK 3111T/C genetic variant influences the daily rhythm of autonomic nervous function: relevance to body weight control.
International journal of obesity (2005) - 1 Feb 2018
Lo M-T, Bandin C, Yang H-W, Scheer F A J L, Hu K, Garaulet M
Abstract excerpt
BACKGROUND/OBJECTIVES: Humans carrying the genetic risk variant C at the circadian CLOCK (Circadian Locomotor Output Cycles Kaput) 3111T/C have been shown to have more difficulties to achieve desired weight loss than TT carriers. We tested the hypothesis that the daily rhythm of autonomic nervous function differs in CLOCK 3111C carriers, leading to reduced effectiveness in weight control. SUBJECTS/METHODS: We...
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