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Article

CYP3A5 polymorphism in Mexican renal transplant recipients and its association with tacrolimus dosing.

Archives of medical research - 1 May 2012

García-Roca Pilar, Medeiros Mara, Reyes Herlinda, Rodríguez-Espino Benjamín Antonio, Alberú Josefina, Ortiz Lourdes, Vásquez-Perdomo Mayela, Elizondo Guillermo, Morales-Buenrostro Luis Eduardo, Mancilla Urrea Eduardo, Castañeda-Hernández Gilberto

Abstract excerpt

BACKGROUND AND AIMS: Variability in CYP3A5 expression associated with differences in tacrolimus bioavailability has been documented. The wild-type allele CYP3A5*1 expresses the functional protein, whereas the CYP3A5*3 allele is a splice variant with a premature stop codon and encodes a truncated nonfunctional protein. The aim of the study was to determine the frequency of CYP3A5*1 and CYP3A5*3 in 291 (124 adults,...

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Source

Identifiers

PMID: 22704849
DOI: 10.1016/j.arcmed.2012.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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