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Article

Mechanisms for nicotine in the development and progression of gastrointestinal cancers.

1 Apr 2012

Abstract excerpt

Long-term smoking is major risk factor for a variety of cancers, including those of the gastrointestinal (GI) tract. Historically, nicotine and its derivatives are well known for their role in addiction, and have more recently been documented for their carcinogenic role in a number of human cancers. The cellular and molecular pathways activated by nicotine mimic physiological and environmental carcinogenesis in...

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Identifiers

PMID: 22701817
DOI: 10.3978/j.issn.2224-4778.2011.12.01

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