Article
Harnessing the potential of adult cardiac stem cells: lessons from haematopoiesis, the embryo and the niche.
Journal of cardiovascular translational research - 1 Oct 2012
Balmer Gemma M, Riley Paul R
Abstract excerpt
Across biomedicine, there is a major drive to develop stem cell (SC) treatments for debilitating diseases. Most effective treatments restore an embryonic phenotype to adult SCs. This has led to two emerging paradigms in SC biology: the application of developmental biology studies and the manipulation of the SC niche. Developmental studies can reveal how SCs are orchestrated to build organs, the understanding of...
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